Gusinzira nigice cyingenzi mubuzima bwa buri munsi bwabantu, bigira ingaruka zikomeye kubuzima bwumubiri nubwenge bwumuntu, imikorere yumubiri nibikorwa byubwenge.Melatonin, imisemburo isohorwa na gineine, igira uruhare runini mugutunganya injyana yo gusinzira no gukomeza gusinzira.Iyi ngingo izasuzuma ingaruka zigenga melatonine ku bitotsi ukurikije ubuvanganzo bw'umwuga.
Imiterere nihame rya melatonin
Melatonin ni ubwoko bwa hormone indole ikomatanya kandi ikarekurwa na glande ya pituito ya pineine yinyamabere, ifite injyana igaragara.Mubidukikije bifite urumuri ruhagije, retina yumva urumuri kandi ikabuza synthesis ya melatonin no gusohora binyuze muri retina-hypothalamic-pineal axis.Mubidukikije byijimye, retina ntabwo yumva urumuri, kandi iteza imbere synthesis hamwe nisohoka rya melatonine binyuze muri retina-hypothalamic-pineal axis.
Ingaruka za melatonin kumiterere yibitotsi
Melatoniniteza imbere ibitotsi cyane cyane ikorana na reseptor ya melatonine yihariye kugirango igenzure isaha izenguruka kandi ibuze gukanguka.Mwijoro, urugero rwa melatonine ruzamuka, rufasha guhindura isaha yibinyabuzima yumubiri no gusinzira umuntu.Muri icyo gihe, melatonin irashobora kandi gufasha gukomeza gusinzira muguhagarika kubyuka.Ubushakashatsi bwerekanye ko ingaruka za melatonine zigenga ibitotsi zifitanye isano rya bugufi nigihe cyo kuyobora.
Bitatu, indwara ya melatonin n'indwara ziterwa no gusinzira
Kudakwirakwiza melatonine birashobora gutera indwara yo gusinzira nizindi ndwara ziterwa no gusinzira.Kurugero, ibibazo byo gusinzira nko kudasinzira, syndrome de shift, hamwe ningorabahizi zo kumenyera indege bifitanye isano no guhungabanya injyana ya melatonin.Byongeye kandi, ubushakashatsi bumwe bwerekanye ko umusaruro wa melatonine udahagije ushobora nanone kongera ibyago byo kurwara Alzheimer, depression ndetse nizindi ndwara.
umwanzuro
Uruhare rwa melatonine mugutunganya ibitotsi rwizwe cyane mubyiciro byinshi.Nubwo, nubwo uruhare rwa melatonine rufite uruhare runini mugutunganya ibitotsi, haracyari ibibazo byinshi bigomba gushakishwa.Kurugero, uburyo bwihariye bwibikorwa bya melatonin buracyakeneye kwigwa;Ingaruka ya melatonine mugutunganya ibitotsi irashobora kuba itandukanye mubantu batandukanye (nkabantu bafite imyaka itandukanye, igitsina nubuzima bwabo).Kandi ushishoze imikoranire hagati ya melatonin nibindi bintu byubuzima bwa physiologique na psychologique.
Byongeye kandi, birakwiye ko tumenya ko nubwo gukoresha melatonine mugutunganya ibitotsi byerekana ibyiringiro, umutekano wacyo, gukora neza no gukoresha neza biracyakeneye ibindi bimenyetso byubuvuzi.Kubwibyo, icyerekezo cyubushakashatsi kizaza gikubiyemo gukora ibizamini byinshi byamavuriro kugirango hamenyekane ingaruka nyayo ya melatonine mugutezimbere ibitotsi nindwara ziterwa nayo.
Indanganturo
Bachman, JG, & Pandi-Perumal, SR (2012) .Melatonin: imiti ivura ibirenze ibitotsi. Ikinyamakuru cyubushakashatsi bwa pinusi, 52 (1), 1-10.
Brayne, C., & Smythe, J.
Igihe cyo kohereza: Nzeri-27-2023