Amakuru y'ibicuruzwa
Ibibabi bya Mulberry DNJ ni alkaloide isanzwe, izina ryigishinwa ni 1-deoxynojirimycin.Ni glucose ikomeye ya metabolizing enzyme (urugero: α- Glycosidase) inhibitor irashobora gutinza cyane gahunda yo kwangirika kwa polysaccharide, kugabanya agaciro keza ka glucose yamaraso nyuma yo gutangira no guhagarika glucose yamaraso yisonzesha;Nibintu bya "inhibitor factor" mubintu bine bigenzura isukari ya alfa.
1 、 Ingaruka yikibabi cya tuteri DNJ
1. Inzira eshatu zo kugabanya glucose yamaraso
Nka inhibitori ikomeye ya glucose metabolizing enzymes (urugero: α- Glucosidase, hexokinase, glucuronidase na glycogen phosphatase, nibindi), DNJ irashobora gutinza cyane inzira yo kwangirika kwa polysaccharide, kugabanya agaciro keza ka glucose yamaraso nyuma yo gutangira no guhagarika glucose yamaraso yisonzesha.Byongeye kandi, DNJ ifite ingaruka zo gukangurira insuline kunoza insuline.
2. Kugabanya isukari yamaraso nyuma yinyuma.
α- Glucosidase ikwirakwizwa cyane mu mara mato y'abantu kandi igira uruhare runini mu kubora kwa karubone.Bashinzwe kubora kwa oligosaccharide nka oligosaccharide mu biryo muri monosaccharide, nka glucose.Iyi glucose yinjira mu mubiri inyuze mu rukuta rw'amara, itera kwiyongera gukabije kw'amaraso glucose.DNJ ni karemano kandi ikomeye α- Inhibitori ya Glucosidase ihuza irushanwa mu mara mato α- Ubusabane bwa glucosidase burenze ubwa oligosaccharide nka sucrose na maltose α- Glucosidase ifitanye isano ikomeye kandi igabanya oligosaccharide na α- Birashoboka ko glucosidase ihuza , kugirango rero ubuze kwangirika kwa fructose muri glucose, kandi isukari nyinshi ntizakirwa kandi yoherejwe mu mara manini.Bitewe n'ingaruka za DNJ, glucose nkeya yinjira mumaraso, glucose yamaraso rero ikwiye kubungabungwa kurwego rwiza.
3. Kwiyiriza ubusa glucose yamaraso.
DNJ ifite ibikorwa byo guhagarika fosifori ya glycogene, ishobora kugabanya umuvuduko w’umwijima glycogene muri glucose, kugirango uhagarike glucose yamaraso yisonzesha.Glucose "irenze" mu mubiri w'umuntu ibikwa mu mwijima mu buryo bwa glycogene.Glycogene irashobora gucikamo glucose ikozwe na fosifori ya glycogene ikarekurwa mumaraso kugirango ibikenerwa byimitsi nibindi bikorwa byingingo.Glycogen ni imwe mu nkomoko y'ingufu zikora imyitozo ngororamubiri.Hamwe no guhinduka hagati ya glycogene na glucose, glucose yamaraso yabantu basanzwe iringaniye.Ku barwayi ba diyabete, kubera imikorere mibi ya glucose metabolism, glycogene nyinshi izacika muri glucose, bikaviramo kwiyongera kudasanzwe glucose yamaraso yo kwiyiriza ubusa.DNJ irashobora guhagarika ibikorwa bya fosifori ya glycogene kandi ikarinda kwiyongera kwa glucose yamaraso iterwa no kwangirika kwa glycogene ikabije muri glucose, kugirango ihagarike glucose yamaraso.
4. Kunoza insuline.
DNJ irashobora kunoza ibimenyetso birwanya insuline ikosora metabolisme ya lipide, igabanya umuvuduko wa glucose no gukangurira insuline.Kurwanya insuline bivuga impamvu zitandukanye (cyane cyane zirimo ibintu bikomoka ku moko n'umubyibuho ukabije), bigabanya imikorere ya insuline itera glucose gufata no kuyikoresha, kandi umubiri ugatanga insuline nyinshi.Kurwanya insuline bitera hyperinsulinemia kugirango igumane glucose yamaraso mu mubiri.Niba umubiri wumuntu uri mumwanya wo kurwanya insuline igihe kirekire, bizongera cyane umutwaro wa pancreas.Irashobora gutera pancreas gusohora kunanirwa imikorere ya insuline hanyuma igatera diyabete.DNJ irashobora kunoza ibimenyetso birwanya insuline ikomeza glucose yamaraso meza, ikosora metabolisme ya lipide no kongera insuline.
2 fields Gukoresha imirima yamababi ya DNJ
Ibibabi bya Mulberry bivamo amababi ya DNJ byashyizwe ku rutonde nkingaruka zifasha hypoglycemic kandi ikoreshwa cyane mubiribwa byubuzima.
Ibipimo byibicuruzwa
| UMWUGA W'ISHYAKA | |
| izina RY'IGICURUZWA | Ibibabi bya Mulberry DNJ |
| CAS | 19130-96-2 |
| Imiti yimiti | C6H13NO4 |
| Brand | Hande |
| Muruganda | Yunnan Hande Bio-Tech Co, Ltd. |
| Country | Kunming,China |
| Hashyizweho | 1993 |
| BAMAKURU ASIC | |
| Synonyme | (2r, 3r, 4r, 5s) -2-hydroxymethyl-3,4,5-trihydroxypiperidine;5-piperidinetriol, 2- (hydroxymethyl) -, (2r- (2alpha, 3beta, 4alpha, 5beta)) - 4; bay-h5595; moranolin; moranoline; (+) - 1-DEOXYNOJIRIMYCIN; 1-DEOXYNOJIRIMYCIN; (2R, 3R, 4R, 5S) -2-. |
| Imiterere |  |
| Ibiro | N / A. |
| HS Kode | N / A. |
| UbwizaSpecification | Ibisobanuro bya sosiyete |
| Certificates | N / A. |
| Suzuma | Guhitamo ukurikije ibyo abakiriya bakeneye |
| Kugaragara | Ifu yera |
| Uburyo bwo gukuramo | Yakuwe mumababi ya tuteri nigishishwa cyumuzi |
| Ubushobozi bwa buri mwaka | Guhitamo ukurikije ibyo abakiriya bakeneye |
| Amapaki | Guhitamo ukurikije ibyo abakiriya bakeneye |
| Uburyo bwo Kwipimisha | HPLC |
| Ibikoresho | Kugwizaubwikorezis |
| PaymentTerms | T / T, D / P, D / A. |
| Other | Emera ubugenzuzi bwabakiriya igihe cyose;Fasha abakiriya kwiyandikisha kugenga. |
Tanga ibicuruzwa
1.Ibicuruzwa byose byagurishijwe nisosiyete ni ibikoresho byarangije igice.Ibicuruzwa byibanda cyane cyane kubabikora bafite ibyangombwa byo gukora, kandi ibikoresho fatizo ntabwo aribicuruzwa byanyuma.
2.Ibishobora kuba byiza nibisabwa mugutangiza byose biva mubitabo byatangajwe.Umuntu ku giti cye ntabwo asaba gukoresha mu buryo butaziguye, kandi kugura kugiti cye byanze.
3.Amashusho nibicuruzwa byamakuru kururu rubuga bireba gusa, kandi ibicuruzwa nyirizina bizatsinda.
