Ese Melatonin ashobora gufasha gusinzira?

Muri uyu muvuduko mwinshi, injyana nini hamwe nihuta ryimibereho yabantu, abantu bamwe bakunze gutinza igihe cyo gusinzira nijoro, bigatuma bigorana gusinzira, bikaviramo indwara zimwe na zimwe. Tugomba gukora iki? Niba hari ikibazo, hazabaho kuba inzira yo gukemura ikibazo.

Kuri ubu abantu benshi bumvamelatonin. fasha gusinzira.
Nk’uko imibare y’umuryango w’ubuzima ku isi ibigaragaza, umubare w’ibibazo by’ibitotsi ku isi ni 27%, bikaba bibaye ku mwanya wa kabiri mu ndwara zo mu mutwe zikunze kugaragara ku isi. Hafi y’umuntu umwe kuri batatu afite ibibazo byo gusinzira naho umwe kuri 10 yujuje ibisabwa kugira ngo asuzume kudasinzira. Raporo yashyizwe ahagaragara n’ishyirahamwe ry’ubushakashatsi bw’ibitotsi mu Bushinwa yerekana ko abantu barenga miliyoni 300 mu Bushinwa bafite ikibazo cyo gusinzira, mu gihe urugero rwo kudasinzira ku bantu bakuru ruri hejuru ya 38.2%.

None se Melatonin ashobora gufasha rwose gusinzira? Ni izihe ngaruka?
### Reka turebe melatonin n'uruhare rwayo.
Melatonin (MT) ni imwe mu misemburo isohorwa na glande ya pineal.Melatonin ni iy'imvange ya indole heterocyclic.Izina ryayo ya chimique ni N-acetyl-5 metoxytryptamine, izwi kandi nka pinealoxin. Nyuma ya synthesis ya melatonin, ibikwa muri glande ya pinusi. Ibyishimo bya Sympathetic byinjiza ingirabuzimafatizo ya pineal kugirango irekure melatonine. Ururenda rwa melatonine rufite injyana igaragara ya circadian, ibuzwa kumanywa kandi ikora nijoro.
Melatonin irashobora kubuza hypothalamic pituitar gonadal axis, kugabanya ibiri muri gonadotropine irekura imisemburo, gonadotropine, imisemburo ya luteinizing na estrogene follicular, kandi igakora kuri gonado kugirango igabanye ibiri muri androgene, estrogene na progesterone. Ubushakashatsi buheruka kwerekana bwerekana ko melatonine ari yo. umuyobozi mukuru wa endocrine.Bigenzura ibikorwa bya glande zitandukanye za endocrine mumubiri, bityo bikagenzura kuburyo butaziguye imikorere yumubiri wacu wose.
Imikorere n'amabwiriza ya Melatonin
1) Guhindura injyana ya circadian
Ururenda rwa Melatonin rufite injyana ya circadian.Kuzuza melatonine bivuye hanze yumubiri birashobora kugumana urwego rwa melatonine mumubiri mukiri muto, guhindura no kugarura injyana ya circadian, ntabwo byongera ibitotsi gusa no kunoza ireme ryibitotsi. umubiri wose, uzamure ubuzima bwiza kandi utinde inzira yo gusaza.Kuko hamwe no gukura kwimyaka, glande ya pinusi iragabanuka kugeza ibarwa, bikaviramo gucika intege cyangwa kubura injyana yisaha yibinyabuzima. Cyane cyane nyuma yimyaka 35, melatonine isohorwa numubiri igabanuka cyane, mugihe impuzandengo yagabanutseho 10 ~ 15% buri myaka 10, bikaviramo guhungabana ibitotsi hamwe nuruhererekane rwimikorere mibi. Kugabanuka kurwego rwa melatonine no kubura ibitotsi nikimwe mubimenyetso byingenzi byubwonko bwabantu gusaza.
2) Gutinda gusaza
Indwara ya pineine yabasaza igenda igabanuka buhoro buhoro, kandi isohoka rya MT rigabanuka uko bikwiye. Ingano ya Mel isabwa ningingo zitandukanye mumubiri ntabwo ihagije, bikaviramo gusaza nindwara. Abahanga mu bya siyansi bita gine pineine isaha yo gusaza.Iyo twongeyeho MT tuvuye hanze, turashobora gusubiza inyuma isaha yo gusaza.
3) Irinde ibikomere
Kubera ko MT ishobora kwinjira mu ngirabuzimafatizo byoroshye, irashobora gukoreshwa mu kurinda ADN ya kirimbuzi. Niba ADN yangiritse, ishobora gutera kanseri. Niba mu maraso harimo Mel ihagije, ntabwo byoroshye kurwara kanseri.
4) Ingaruka zigenga kuri sisitemu yo hagati
Umubare munini wubushakashatsi bwubuvuzi nubushakashatsi bwerekana ko melatonin, nkumusemburo wa endogenous neuroendocrine, ufite amabwiriza ya physiologiya ataziguye kandi ataziguye kuri sisitemu yo hagati, ingaruka zo kuvura indwara ziterwa no gusinzira, kwiheba n'indwara zo mumutwe, n'ingaruka zo gukingira ingirabuzimafatizo.Urugero , melatonin igira ingaruka zo gukurura, irashobora kandi kuvura depression na psychose, irashobora kurinda imitsi, irashobora kugabanya ububabare, kugenga imisemburo irekurwa na hypothalamus nibindi.
5) Kugena sisitemu yumubiri
Mu myaka icumi ishize, ingaruka ziterwa na melatonine kuri sisitemu y’umubiri zashimishije abantu benshi.Abanyeshuri bo mu gihugu ndetse no mu mahanga bagaragaje ko melatonine itagira ingaruka gusa ku mikurire n’iterambere ry’imyanya ndangagitsina, ahubwo inagenga ubudahangarwa bw’urwenya, ubudahangarwa bw'umubiri na cytokine. Kurugero, melatonin irashobora kugenga ubudahangarwa bwa selile na humorale, kimwe nibikorwa bya cytokine zitandukanye.
6) Ingaruka zigenga sisitemu yumutima
Imikorere ya sisitemu yimitsi ifite injyana igaragara yumuzingi hamwe nigitekerezo cyigihe, harimo umuvuduko wamaraso, umuvuduko wumutima, umusaruro wumutima, renin angiotensin aldosterone, nibindi. Urwego rwa serumu melatonin rushobora kwerekana igihe gikwiranye numunsi hamwe nigihe cyumwaka cyumwaka. . Byongeye kandi, ibyavuye mu bushakashatsi byemejwe byemeje ko kwiyongera kwa MT mu ijoro bifitanye isano ribi no kugabanuka kw'imikorere y'umutima n'imitsi; Pineal melatonin irashobora gukumira indwara iterwa no gukomeretsa ischemia-reperfusion, bikagira ingaruka ku kugenzura umuvuduko w'amaraso, bikagenga umuvuduko w'amaraso w'ubwonko, kandi kugenga reaction ya arterière periferique kuri norepinephrine.
7) Byongeye kandi, melatonin igenga kandi uburyo bwo guhumeka bwabantu, sisitemu yumubiri hamwe na sisitemu yinkari.
Igitekerezo cya Melatonin
melatoninntabwo ari ibiyobyabwenge. Irashobora kugira uruhare gusa mu kudasinzira kandi nta ngaruka zo kuvura.Ku bibazo nko kutagira ibitotsi bibi no kubyuka hagati, ntabwo bizagira ingaruka zikomeye zo gutera imbere.Muri ibi bihe, ugomba kwivuza mugihe no kubona imiti ikwiye.
Urashaka kumenya byinshi kuri melatonin? Hande yiyemeje guha abakiriya ibicuruzwa byiza kandi byiza byubuzima bwiza.Dutanga ibicuruzwa byiza bya melatonine byujuje ubuziranenge kandi buhanitse kugirango bigufashe kunoza ibitotsi no kubaho neza buri munsi!