Nigute paclitaxel irwanya kanseri?

Paclitaxel ni diterpenoid yakuwe mu bwoko bwa Taxus, kandi abahanga mu bya siyansi basanze ifite ibikorwa bya antitumor ikomeye mu bushakashatsi bwakozwe.Kugeza ubu,paclitaxelikoreshwa cyane mu kuvura kanseri y'ibere, kanseri y'intanga, kanseri y'ibihaha itari ntoya, kanseri y'urwagashya, kanseri yo mu nda, kanseri yo mu gifu, ikibyimba cyo mu mutwe no mu ijosi, tissue tissue sarcoma n'ibindi bibyimba bibi, kandi ni kimwe mu bikunze kugaragara yakoresheje imiti ya chimiotherapie mubikorwa byubuvuzi.Nigute mubyukuri paclitaxel irwanya kanseri?Reka turebe hepfo.

Nigute paclitaxel irwanya kanseri?Birazwi neza ko mugihe cyo kugabana bisanzwe, selile igabanyijemo ibice bibiri.Chromosome imaze kwigana, spindle filament iyikura mumwanya wambere wambere kugeza kumpande zombi, kandi spindle ikenera depolymerisation ya microtubules nka cytoskeleton kugirango ibeho, Chromosomes irashobora kurangiza mitito gusa yimukira mumigozi ikururwa na spindle na spindle filament, microtubules rero ningirakamaro cyane mukugabana selile.

Mu 1979, umuhanga mu by'imiti Horwitz yavumbuye kopaclitaxelIrashobora guhuza na tubuline no guteza imbere polymerisation ya tubuline kugirango ikore microtubules, bityo ikabuza gutandukana bisanzwe kwa physiologique ya microtubules, bigatuma idashobora gukora spindle na spindle filaments, bigatuma selile Kudashobora gutandukana mubisanzwe birinda kubyara vuba kanseri ya kanseri kandi bitera apoptose ya kanseri.Kubwibyo, mu miti igabanya ubukana, paclitaxel ifatwa nka microtubule inhibitor muri mitose.

Icyitonderwa: Ingaruka zishoboka nibikorwa byasobanuwe muriyi ngingo biva mubitabo byasohotse.

Gusoma kwagutse:Yunnan Hande Biotechnology Co., Ltd. imaze imyaka 28 yibanda ku musaruro wa paclitaxel.Nicyo gihugu cya mbere cyigenga ku isi gikora imiti ikomoka ku bimera paclitaxel ikomoka ku bimera byemejwe na FDA yo muri Amerika, EDQM yo mu Burayi, TGA yo muri Ositaraliya, Ubushinwa CFDA, Ubuhinde, Ubuyapani n’izindi nzego zishinzwe kugenzura igihugu.uruganda.Niba ushaka kuguraYamazaki API,nyamuneka twandikire kumurongo.