Kamere ya Paclitaxel VS Semi-synthique Paclitaxel (I)

Imiti y'ibikoresho

Paclitaxel, nk'imiti igabanya ubukana, ikoreshwa cyane mu gutera inshinge zitandukanye.

Byakozwe cyane cyane no kuvoma bisanzwe hamwe na synthesis.

Nka nkomoko yibihingwa bya paclitaxel isanzwe ikurwa, Taxus Chinensis, ni gake cyane kandi ifite uruziga rurerure rwo gukura, urukurikirane rwuburyo bwa synthesis bwakuwe buhoro buhoro muri paclitaxel binyuze mubushakashatsi nubushakashatsi ku isi, harimo synthesis yose, igice cya kabiri, na synthesis.

Bitewe n'inzira ndende ya synthesis ya chimique, intambwe nyinshi za synthesis, kandi bigoye kugenzura imiterere yimyitwarire, paclitaxel yuzuye ikenera gukoresha imiti ihenze cyane, kandi umusaruro nawo uri muke, udakwiriye kubyara umusaruro mwinshi n’umusaruro w’inganda muri rusange.

Kubwibyo, umubare munini wa paclitaxel ku isoko muri rusange ukorwa no kuvoma bisanzwe amatagisi ahingwa hamwe nuburyo bwa sintetike.

Kamere ya Paclitaxel vs Semi-synthique Paclitaxel

Igice cya 1: Inzira yumusaruro

Paclitaxel:

-Ibikoresho bibisi: Yatewe ibihimbano Yew

-Ibikorwa byo gukuramo: ibikoresho fatizo + inkingi chromatografiya + kongera gukora = ibicuruzwa byarangiye

-Ibikorwa byo gukuramo: reaction yumubiri, nta nzira ya synthesis

Semi-synthique Paclitaxel:

-Ibikoresho bibisi: Yatewe ibihimbano Yew

-Ibikorwa byo gukuramo: ibikoresho fatizo + imiti ya reagent reaction + yibanda kuri kristalisiti + reaction zitandukanye za chimique + recrystallisation = ibicuruzwa byarangiye

-Ibikorwa byo gukuramo: reaction ya chimique

Ku bijyanye n’ikoranabuhanga, paclitaxel karemano ifite intambwe yoroshye yo gukuramo ugereranije na paclitaxel ya kimwe cya kabiri cyogukora hamwe ninyungu nyinshi kurenza paclitaxel ya sem-sintetike mu bijyanye n’umutekano n’umutekano, mu gihe paclitaxel ya sintetike igabanya igiciro cy’iterambere ry’ibicuruzwa ukurikije igiciro n’ibikoresho fatizo. , kandi inatezimbere ibibazo bimwe na bimwe biterwa n'ubuke bwibikoresho fatizo ku isoko.

Ugereranije nuburyo bubiri bwo gukora paclitaxel, paclitaxel karemano ifite umutekano muke numutekano mubikoresho byubuvuzi, iyi ikaba ari imwe mu mpamvu zituma ibigo byinshi byubuvuzi byisoko bikoresha paclitaxel nkibikoresho fatizo.

Yunnan Hande Biotechnology Co., Ltd.yagize uruhare mu gucukura no guteza imbere tagisi mu myaka 30, kandi ibicuruzwa byayo ni paclitaxel karemano, 10-DAB igice cya sintetike paclitaxel, 10-deacetylbaccatin III, docetaxel, cabazitaxel, nibindi. andi makuru yerekeye paclitaxel APIs, nyamuneka twandikire !!! (Whatsapp / Wechat: +86 18187887160)