Kamere ya Paclitaxel VS Semi-synthique Paclitaxel (II)

Yew taxus chinensis ikurwa mubihingwa bisanzwe bidasanzwe, byashyizwe, uruti, uruhu, umuzi birimo ibintu byingenzi aribyo: yew alkali diterpenoid compound, yew ning A na yew, yew ning H, yew, yew ning K, l, yew alkali, jinsong yumuhondo ketone, umusozi uva A, uku gusiga ketone ketone, jinsong kabiri yumuhondo ketone, naphtha, yew, polysaccharide, tannine, umutuku wijimye, nibindi, birashobora kandi kubamo izindi polifenol, acide amino, resin yinkwi, ibintu bidakoreshwa.Paclitaxel ifite anti-leukemia n'ingaruka z'ikibyimba.

Paclitaxel tugiye kuvuga, niwo muti mwiza cyane urwanya kanseri wabonetse kugeza ubu.Yakoreshejwe cyane mu kuvura kanseri y'ibere, kanseri y'intanga, kanseri yo mu mutwe no mu ijosi, kanseri y'ibihaha na benshi izindi kanseri mubuvuzi.

Kamere ya Paclitaxel vs Semi-synthique Paclitaxel

Umwanda:

Paclitaxelikurwa mu mizi, ibiti n'amababi ya Taxus chinensis.Nyuma ya chromatografiya yinkingi no kongera kuyisubiramo, inzira yose ni ugukuramo umubiri no kwezwa nta reaction yimiti. Umwanda urimo urimo ibikomoka ku gihingwa ubwacyo, kandi nta mwanda uhari. yazanwe na synthesis ya chimique.Niyo mpamvu, gukosora umwanda wa paclitaxel karemano byizwe byuzuye kandi birashobora kugenzurwa muri iki gihe.

Semi-synthique paclitaxelifite synthèse chimique kurusha iyisanzwe mubikorwa byayo, kandi inkomoko yayo yanduye nayo irenze iyimiterere karemano, harimo bimwe byakuwe mubihingwa, hamwe n’umwanda ukomoka kuri synthesis ya chimique reaction.Ikindi kandi, reaction ya chimique nayo izatera kuvuka kwa bamwe ibishobora kuba umwanda.Muri iki gikorwa, ubwinshi nubwoko bwimyanda ihora ihinduka.Nuko rero, igice cya sintetike paclitaxel gifite ubushobozi buke bwo kugenzura imyanda, kandi umwanda mushya ugomba guhora wiga mubikorwa byumusaruro.Impanuka zakozwe nuburyo butandukanye bwo gukora nabwo. bitandukanye cyane, kandi isesengura ryihariye rirakenewe.

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