Ingaruka ninshingano za paclitaxel

Paclitaxel ikomoka muri Taxus chinensis kandi nikintu cya mbere kiboneka kigira ingaruka mbi ku ngirabuzimafatizo.Imiterere ya paclitaxel iragoye, kandi ubuvuzi bwayo bugaragarira cyane cyane mu kuvura kanseri y'ibere, kanseri y'ibihaha, na kanseri y'intanga.Yamazakini metabolite ya kabiri yakuwe mubishishwa bya Taxus chinensis naba chimiste bo muri Amerika, bifite ingaruka nziza zo kurwanya ibibyimba.Reka turebe efficacy ninshingano za paclitaxel.

Imikorere n'uruhare rwapaclitaxel

1. Ingaruka zo kurwanya ibibyimba

Paclitaxel ni imiti igabanya ubukana bwa microtubule.Paclitaxel irashobora guteza imbere inteko ya microtubule iteza imbere polymerisation ya spinosomal tubulin subunits, ndetse no mubunzi basabwa guteranya microtubule isanzwe (nka GTP, guanosine triphosphate, nibindi)., nibindi) birashobora kandi kugira iyi ngaruka, bikavamo gushiraho microtubules idakora, ihamye.

2. Ingaruka zo kurwanya kanseri

Paclitaxel igira ingaruka za anticancer kumirongo ya selile mbi ya sarcoma, leukemia na melanoma mbi.Paclitaxel kandi niwo muti wo ku murongo wa mbere ku bagore bafite kanseri y'ibere na kanseri y'intanga.Paclitaxel irashobora guhambira kuri microtubules, ishobora "gukonjesha" no gukumira itandukaniro rya chromosomes mugihe cyo kugabana selile, ishobora kwica kanseri ya kanseri.

3. Kuvura rubagimpande

Ubushakashatsi bwerekanye ko paclitaxel yemejwe na FDA yo kuvura rubagimpande ya rubagimpande, kandi gel ya paclitaxel ni ingingo yibanze yapaclitaxel kuvura rubagimpande ya rubagimpande.

Icyitonderwa: Ingaruka zishoboka nibikorwa byasobanuwe muriyi ngingo biva mubitabo byasohotse.

Gusoma kwagutse:Yunnan Hande Biotechnology Co., Ltd. imaze imyaka 28 yibanda ku musaruro wa paclitaxel.Nicyo gihugu cya mbere cyigenga ku isi gikora imiti ikomoka ku bimera paclitaxel ikomoka ku bimera byemejwe na FDA yo muri Amerika, EDQM yo mu Burayi, TGA yo muri Ositaraliya, Ubushinwa CFDA, Ubuhinde, Ubuyapani n’izindi nzego zishinzwe kugenzura igihugu.uruganda.Niba ushaka kuguraYamazaki API,nyamuneka twandikire kumurongo.