Paclitaxel ， nk'umuti wa mbere wa chimiotherapie wakuwe mu bimera karemano still uracyari umwe mu miti isanzwe muri chimiotherapie yibibyimba kugeza na nubu.Yamazakini imiti isanzwe irwanya ibibyimba yakuwe mu bimera bya tagisi ， kandi uburyo bwayo bwo gukora ni uguteza imbere microtubule igamije gukumira mitose ya selile. Ni umwe mu miti myiza irwanya ibibyimba ku isoko rya farumasi ， kandi harakenewe cyane ku isoko mpuzamahanga rya farumasi.Paclitaxel igabanijwemo paclitaxel karemano na paclitaxel ya kimwe cya kabiri. Reka turebe uruhare rwa 10-Dab Semi-Synthetic Paclitaxel mu nyandiko ikurikira.
10-Dab Semi-Synthetic Paclitaxelni igice cya sintetike ya paclitaxel ikomoka hamwe nibikorwa bya farumasi bisa na paclitaxel karemano.Paclitaxe ni umuti urwanya kanseri ， ushobora gukoreshwa mu kuvura ubwoko butandukanye bwa kanseri ， nka kanseri y'ibere cancer kanseri y'intanga cancer kanseri y'ibihaha na kanseri yo mu gifu. Gutegura ya precursor 10-DAB ya paclitaxel ikoresheje uburyo bwa sintetike yuburyo bushobora kongera umusaruro nubuziranenge bwa paclitaxel ， kugabanya ibiciro byumusaruro ， kandi bigatuma paclitaxel iramba kandi yubukungu. Byongeye kandi ， 10-DAB ubwayo ifite ibikorwa bya farumasi ， nkingaruka zayo zo kubuza kuri selile zimwe na zimwe.
10-Dab Semi-Synthetic PaclitaxelIrashobora gukora imirimo ningaruka nyinshi ， ntabwo ari igicuruzwa giciriritse cyubuvuzi ， ariko nanone nkigicuruzwa kibisi cyubuvuzi.Ku bigaragara ， bigaragara nka kirisiti yera.Ni ikoreshwa cyane mubikorwa bya farumasi kandi birashobora ikoreshwa nkibikoresho fatizo byubuvuzi has bifite ingaruka nziza cyane mugukora imiti yagutse ya virusi.
Igihe cyo kohereza: Jun-01-2023