Kuki paclitaxel ihujwe na Albumin idakeneye kubanzirizwa?

Kugeza ubu, hari ubwoko butatu bwimyiteguro ya paclitaxel ku isoko mu Bushinwa, harimo inshinge za paclitaxel, Liposomal paclitaxel na paclitaxel ihujwe na Albumin. Inshinge zombi za paclitaxel hamwe na Liposomal paclitaxel yo gutera inshinge zikeneye kuvurwa hakoreshejwe imiti yo kwitegura allergie, ariko kuki Albumin- paclitaxel iboshye ntabwo ikeneye kuvurwa? Reka turebe ibi bikurikira.

Kuki paclitaxel ihujwe na Albumin idakeneye kubanzirizwa? Noneho reka twumve uburyo bwa allergie yuburyo butatu bwa paclitaxel.

1.Gutera inshinge

Kugirango wongere amazi ya paclitaxel, umusemburo wo gutera paclitaxel ugizwe namavuta ya polyoxyethylene ya castor hamwe na Ethanol. kandi bigatera allergie reaction. Mbere yo gukoresha ivuriro, glucocorticoide na antihistamine bigomba gukoreshwa mukwitegura.

2.Liposomal paclitaxel

Liposomal paclitaxel ahanini ni liposomes ya fosifolipide bimolecular ifite diameter ya 400 nm ikorwa na lecithine na cholesterol ku rugero runaka.Bidafite amavuta ya polyoxyethylene castor na Ethanol yuzuye ishobora gutera allergie.

Nyamara, ubundi bushakashatsi bwerekanye ko paclitaxel ubwayo ishobora no gutera hypersensitivite, ifitanye isano nogukora kwimikorere yubudahangarwa bwahujwe na basofili, IgE na IgG.Ariko ugereranije no guterwa paclitaxel, igipimo cyayo cya allergique ni gito.Ubu, Liposomal paclitaxel iracyafite bisaba kwiyitirira allergique mbere yo kuyikoresha.

3.Albumin-iboshye paclitaxel

Paclitaxel ihujwe na Albumin, hamwe na alubumu yumuntu nkuwitwara, ifite ibyiza byo kubora byoroshye muri vivo, kwirundanyiriza ibiyobyabwenge byinshi mubyimba, kwibasira cyane hamwe na chimiotherapie ikora neza.

Mu cyiciro cya I, II cyangwa III ubushakashatsi kuri paclitaxel ihujwe na alubumu, nubwo nta kwitegura kwakozwe, nta reaction ya hypersensitivite yabonetse.Impamvu ishobora kuba ari uko nta mavuta ya castor polyoxyethylene kandi ibirimo tagisi yubusa mumaraso ari bike .Nuko rero, kwitegura mbere yubuyobozi bwa albumin iboshye paclitaxel ntabwo byemewe muri iki gihe.

Icyitonderwa: Ubushobozi bushoboka nibisabwa byatangijwe muriyi ngingo byose biva mubitabo byasohotse.

Yunnan Hande Biotechnology Co, Ltd yagiye ikora ibijyanye no gukorapaclitaxel APImu myaka irenga 20, kandi ni umwe mu bakora uruganda rwigenga ku isi rwa paclitaxel API, imiti ikomoka ku bimera ikomoka ku kurwanya kanseri, yemejwe na FDA yo muri Amerika, EDQM yo mu Burayi, TGA yo muri Ositaraliya, CFDA y’Ubushinwa, Ubuhinde, Ubuyapani n’izindi nzego zishinzwe kugenzura igihugu. .Hande ntishobora gutanga ubuziranenge gusapaclitaxel ibikoresho fatizo, ariko kandi na serivise yo kuzamura tekinike ijyanye na formulaire ya paclitaxel. Kubindi bisobanuro, nyamuneka twandikire kuri 18187887160.